The show opens with the mysterious suicide of housewife Mary Alice Young on a beautiful day in the suburbs, on a street called Wisteria Lane. As her friends grapple with the mystery of her death, they also deal with their own issues: Susan competes with neighbor Edie for the affections of new resident Mike. Gabrielle tries to hide her affair with gardener John from her husband Carlos, and Bree and Lynette both deal with problems concerning their children and their marriages.