Larry Daley is a security guard at The Museum of Natural History. He is handed an over-sized flashlight and a dog-eared instruction manual, then left all alone in the eerily quiet, cavernous museum. At his wit's end, Larry must recruit the help of historical heavyweight Teddy Roosevelt just to survive the night. Facing the possibility of losing his job and letting down his son Nick yet again, Larry must wage an incredible battle to save the museum, hoping to become at last the bold, adventurous dad he's always wanted to be. The man who's been forever waiting for his moment of greatness just found it.